Nutricoll Nordic Marine Collagen 

Fish derived collagen peptides are receiving more and more attention due to their favourable characteristics and fewer consumer reservations compared to mammal-derived ingredients.

Seagarden has developed a production line for marine-based collagen peptides to cater the growing demands of the nutraceutical and cosmetic industries worldwide. Nutricoll Nordic Marine Collagen is exclusively produced from deep-sea cod skin (Gadus morhua), harvested from the crystal clear waters of the North Atlantic Ocean. This provides the purest source of high quality and 100% natural collagen peptides available on the market.

Nutricoll Nordic Marine Collagen stands out due to its low molecular weight resulting in improved digestibility and increased bioavailability. Nutricoll Nordic Marine Collagen is the ideal bio-active ingredient to include in a wide range of applications for health, sports, beauty and cosmetics. 

Seagarden offers Nutricoll Nordic Marine Collagen peptides with an average molecular weight of 3 kDa and 6 kDa. kDa is an abbreviation for kilodalton which describes a unit of molecular mass consisting of 1000 daltons and it is the standard unit used to represent the weight of large molecules such as proteins. The 3 kDa variant has smaller particles and lower molecular weight and thus better bioavailability compared to 6 kDa. This variant is therefore suitable for tablets and stronger flavoured products as the taste is more profound. Nutricoll Nordic Marine Collagen of 6 kDa has almost no taste and smell and is therefore excellent to use in natural pure products.

Collagen peptides are a hydrolysed form of collagen, which is a unique oligopeptide supplying the necessary amino acids for the development of collagen in human connective tissues and skin. Through an enzymatic hydrolysis process, the product loses its gelling effect and becomes water-soluble. 

Collagen peptides are highly digestible and suitable as an oral supplement. Studies show that collagen peptides have a better bioavailability in the human body than gelatine, due to the difference in molecular size. Our product is suitable for those who do not use collagen from traditional bovine and porcine sources. 

Clinical studies recommend a daily dose of 10 g, for a minimum of three months, for best effect. Followed by a daily maintenance dose of 5 g. Since it is readily soluble in water, it can be mixed with beverages such as water, juice or other liquids, or in foods such as yoghurt, porridge or cereals.

Main features of Nutricoll Nordic Marine Collagen Peptide

• 100% pure natural fish collagen peptide from high quality wild cod

• Natural, raw materials harvested from the crystal clear waters of the North Atlantic Ocean

• Mild taste and smell

• Good and fast solubility

• Protein content more than 90%

• Low heavy metal content 

• Bio-available protein that is easily digestible

• Free from artificial additives and preservatives

• MSC approved raw materials – sustainable fisheries

Nutricoll Marine Collagen Peptide is available in bulk, sticks and tablets. Our product development team will assist with product development.

Applications

“Beauty from within”                       Tablets, shots, shakes, snacks

Functional sport                               Shots, sport-shakes, smoothies, nutri-bars, soups, snacks

Facial, beauty and hair                    Face masks, creams, serums, lotion, hair products

Pharmaceuticals                              Tablets, shots, nutri-bar, gels

Properties

Appearance                                     Fine light powder

Raw material                                   Cod skin (Gadus morhua)

Protein                                              > 90 %

pH                                                      5,0 – 7,0

Average molecular weight             ≥ 3000 and 6000 kD

 

Why are nordic marine collagen peptides unique?

The absorption of marine collagen peptides into the body is proven to be to 1.5 times more efficient than collagen from bovine or porcine sources and their bio-availability is much superior. One of the advantages of fish collagen is that it has a particular high content of the amino acids glycine, proline and hydroxyproline. The amino acids stimulate cells in the skin, bones and connective tissues and leads to the production of new collagen.

Glycine contributes to the synthesis of collagen as well as a variety of other proteins. It can also protect organs and tissues by general inflammatory conditions.

Proline is the precursor of hydroxyproline, which is involved in the formation of collagen, tendons and ligaments. Proline is therefore important in the treatment of osteoarthritis. Proline is depending on vitamin C for the formation of collagen. The proline productions in the body increases for instance with injuries and after exercise where it builds up damaged muscle fibres. This means that marine collagen peptides can be helpful in the restitution phase after exercise.

Hydroxyproline is the hydroxylation of proline and it is depending on vitamin C. Therefore, lack of vitamin C could give unstable collagen molecules and affect collagen in the body.

Several studies have proven the impact of marine collagen peptides on personal appearance and the musculoskeletal system.

Anti-aging effect on human skin

Marine Collagen hydrolysates has an anti-aging effect on human skin. A recent clinical trial demonstrated a significant increase in skin elasticity in a group of women aged 35-55 years (1).

Reducing skin wrinkles

The same group of scientists from the University Of Kiel, Germany, also demonstrated a significant reduction in skin wrinkles after daily consumption of a collagen hydrolysate (1).

Increasing the skin moisture level

A comprehensive study of the effect of oral collagen peptide supplement on skin-aging involving clinical trials with Japanese and Caucasian women showed good effect on skin moisturisation. The fish collagen peptides were shown to increase the skin moisture level by 12% in a period of 8 weeks. A consistent increase in the skin collagen density over 12 weeks was confirmed by increased dermal echogenicity. Ex vivo studies confirmed the results of the clinical trials and showed an increased amount of water-binding glycosaminoglycans and collagen content in human skin explants incubated with fish collagen peptides(2).

Protecting hair against chemical damage

In a clinical study with 62 test subjects, fish-derived collagen peptides were shown to have a positive effect on the skin moisture content. The same study documented the transdermal penetration ability of those collagen peptides and showed increased abilities for fish collagen peptides in the range of 3.5-4.5 kDa. in hair, the collagen peptides diffuse into the fibrous hair cells (3).

Added value for the musculoskeletal system

Products containing active collagen peptides have long been marketed in the US and European pharmaceutical and food markets. Many scientific and preclinical studies show various positive effects on tendon flexibility, ligament stability, muscle and bone integrity and bone metabolism. Another study investigated the effect of specific fish-derived collagen peptides on collagen expression, post-translational modification and mineralisation in an osteoblastic cell culture. Fish collagen peptides were shown to upregulate the gene expression of collagen-modifying enzymes and this effect led to an increased collagen synthesis and positive effects on collagen quality and matrix mineralisation in the osteoblasts (4).

Another study researched the effects of protein supplements in the form of type 1 collagen peptides in combination with resistance training in older men with sarcopenia. The results showed that, compared with placebo, a collagen supplement in combination with resistance training further improved body composition by increasing the fat-free mass and muscle strength, and reducing fat mass in elderly men with sarcopenia (5).

Specific collagen peptides proved to significantly increase the expression of collagen types 1 and 3 in fibroblasts from ligaments and tendons of humans. The study concluded that collagen peptides may therefore be an option to treat and prevent changes in ligaments and tendons (6).

For more information about Marine Collagen please read our research summary by Dr. Ilka Czech, Research and Development Director.

Collagen Peptides_Source, Properties and Benefits_Review Feb2016

 

References:

1. Proksch, E., et al. “Oral intake of specific bioactive collagen peptides reduces skin wrinkles and increases dermal matrix synthesis.” Skin pharmacology and physiology 27.3 (2014): 113-119.

2. Asserin, Jérome, et al. “The effect of oral collagen peptide supplementation on skin moisture and the dermal collagen network: evidence from an ex vivo model and randomized, placebo‐controlled clinical trials.” Journal of cosmetic dermatology 14.4 (2015): 291-301.

3. Chai, HJ., Li, JH., Huang, HN., Li, TL., Chan YL., Shiau, CY., Wu, CJ. (2010) Effects of size and conformations of fish-scale collagen peptides on facial skin qualities and transdermal penetration efficiency. Journal of Biomedicine and Biotechnology 2010, 1-8.

4. Yamada, Shizuka, et al. “Effects of fish collagen peptides on collagen post-translational modifications and mineralization in an osteoblastic cell culture system.” Dental materials journal 32.1 (2013): 88-95.

5. Zdzieblik, Denise, et al. «Collagen peptide supplementation in combination with resistance training improves body composition and increases muscle strength in elderly sarcopenic men: a randomised controlled trial.» British Journal of Nutrition 114.08 (2015): 1237-1245.

6. Schunck, M., & Oesser, S. (2013). Specific collagen peptides benefit the biosynthesis of matrix molecules of tendons and ligaments. Journal of the International Society of Sports Nutrition, 10(Suppl 1), P23.